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Parallel chronicles

200 events of six sciences
on one axis

Physics, chemistry, astronomy, biology, medicine and mathematics — from Babylonian tablets to the Higgs boson. Each of the 200 events opens on click. All lanes are on by default. Click a chip to hide a discipline; click again to bring it back. “All disciplines” turns every lane on. Zoom in (the + / buttons, or Ctrl + mouse wheel) and event names appear on the lanes.

from 1800 BCE to 2022 12 eras 200 events
Discipline:
100%
Text list: all 200 events (for reading and search)

Era I. Ancient Civilizations: The Origins of Knowledge (before ~600 BCE)

~600 BCE — Thales of Miletus studies magnetism and static electricity

Description: The word “electricity” comes from the Greek name for amber, which Thales experimented with.

~2000 BCE — Babylonian priests keep systematic observations of the sky

Description: Babylonian observational tablets became the foundation for many later astronomical systems, including the Greek one.

~1700 BCE — The Ebers Papyrus records the medical knowledge of ancient Egypt

Description: The Ebers Papyrus contains more than 700 recipes and formulas, including descriptions of tumors.

~1800 BCE — The Babylonian tablet Plimpton 322 records Pythagorean triples

Description: Plimpton 322 shows that the Babylonians knew the Pythagorean theorem more than a thousand years before Pythagoras.

~1650 BCE — The Rhind Papyrus records the mathematical knowledge of ancient Egypt

Description: The Rhind Papyrus is essentially the oldest known mathematics textbook, including problems and their solutions.

Era II. Greek and Hellenistic Science (600–30 BCE)

~450 BCE — Democritus formulates the atomistic hypothesis of the structure of matter

Description: The word “atom” itself comes from the Greek for “indivisible” — that is how Democritus pictured the smallest particle of matter.

~250 BCE — Archimedes formulates the law of the lever and the principle of buoyancy

Description: According to legend, Archimedes made the discovery in his bath and ran into the street shouting “Eureka!”

~300 BCE — Alchemical traditions take shape in the Alexandrian school

Description: The word “alchemy” itself is thought to come from the Arabic al-kīmiyā, which in turn goes back to an ancient name for Egypt.

~600 BCE — Thales, according to tradition, predicts a solar eclipse

Description: Thales’s eclipse prediction, according to legend, halted a battle between the Lydians and the Medes.

~350 BCE — Aristotle argues for a geocentric model of the world

Description: Aristotle’s geocentric model dominated European science for nearly two millennia.

~240 BCE — Eratosthenes calculates the circumference of the Earth

Description: Eratosthenes’s calculation differs from the modern value of Earth’s circumference by only a few percent.

~150 BCE — Hipparchus compiles one of the first star catalogs

Description: Hipparchus’s catalog contained more than 800 stars, with their brightness indicated.

~300 BCE — Aristotle systematizes the animal world in History of Animals

Description: Aristotle’s work describes and classifies more than 500 species of animals.

~300 BCE — Theophrastus lays the foundations of scientific botany

Description: Theophrastus is often called the “father of botany” — he described more than 500 plant species.

~400 BCE — Hippocrates formulates medical ethics and the humoral theory of disease

Description: Hippocrates is considered the author of an oath that, in modified form, medical school graduates still take today.

~600 BCE — Thales introduces deductive proof into geometry

Description: Thales, according to tradition, proved the theorem that an angle inscribed in a semicircle is a right angle.

~530 BCE — Pythagoras and his school develop number theory

Description: The Pythagoreans believed that the entire universe is structured on numerical relationships.

~300 BCE — Euclid writes the Elements — a systematization of geometry

Description: Euclid’s Elements remained the model of mathematical proof for more than two thousand years and is one of the most published books in history.

~250 BCE — Archimedes calculates the number π by the method of exhaustion

Description: Archimedes calculated π to several digits without having a decimal number system.

Era III. Rome, India, China: Parallel Traditions (30 BCE – 500 CE)

~150 CE — Ptolemy systematizes the geocentric model of the world in the Almagest

Description: The Almagest remained the principal astronomical textbook of Europe and the Arab world for more than 1,400 years.

~150 CE — Ptolemy completes the Almagest

Description: The Almagest remained the principal astronomical work of Europe and the Islamic world for more than 1,400 years.

499 CE — The Indian astronomer Aryabhata describes the Earth’s rotation on its axis

Description: Indian astronomy developed largely independently of the Greek and Arabic traditions.

~150 CE — Galen systematizes the anatomical and physiological knowledge of antiquity

Description: Galen’s writings remained Europe’s chief medical authority for more than 1,300 years, despite numerous errors.

~200 CE — Diophantus lays the foundations of algebra in the Arithmetica

Description: Diophantus’s Arithmetica later inspired Fermat to formulate his famous Last Theorem.

Era IV. The Islamic Golden Age and the Early Middle Ages (500–1100)

1021 — Ibn al-Haytham publishes the Book of Optics, laying foundations for experimental science

Description: In the West, Ibn al-Haytham was known as Alhazen — his work was translated into Latin and influenced Kepler and Newton.

8th century — Jabir ibn Hayyan lays the foundations of experimental alchemy

Description: In the West, Jabir ibn Hayyan was known as Geber — the chemical term “Geberism” was later named in his honor.

964 — Al-Sufi describes the Andromeda Nebula in the Book of Fixed Stars

Description: Al-Sufi’s observations anticipated telescopic discoveries of nebulae by nearly seven centuries.

1054 — Observers in China and the Middle East record a supernova outburst

Description: The remnant of that 1054 supernova is known today as the Crab Nebula.

1025 — Ibn Sina completes The Canon of Medicine

Description: Ibn Sina’s Canon remained a required textbook in European universities until the 17th century.

628 — Brahmagupta formulates rules for operations with zero and negative numbers

Description: Brahmagupta was one of the first mathematicians to give a rigorous definition of operations with the number zero.

820 — Al-Khwarizmi writes a treatise on algebra that gave the field its name

Description: The word “algebra” itself comes from the title of his treatise, al-jabr.

9th–10th centuries — The Hindu–Arabic numeral system spreads throughout the Islamic world

Description: Zero as a digit in its own right reached Europe through this numeral system.

Era V. Medieval Universities and Scholasticism (1100–1450)

~1250 — Albertus Magnus systematizes observations on the properties of metals

Description: Albertus Magnus was probably one of the first to isolate pure arsenic as a distinct substance.

1420s — Ulugh Beg builds one of the largest medieval observatories in Samarkand

Description: Ulugh Beg’s observatory could measure star positions with an accuracy unmatched for centuries.

1202 — Fibonacci introduces Europe to the Hindu–Arabic numeral system

Description: Fibonacci introduced Hindu–Arabic numerals to Europe through a book devoted mainly to practical problems of trade.

Era VI. The Renaissance and the Dawn of the Scientific Revolution (1450–1600)

1543 — Copernicus publishes a heliocentric model of the world

Description: Copernicus’s work was published shortly before his death and initially attracted little attention from the Church.

1589–1592 — Galileo conducts experiments on falling bodies

Description: The legend of dropping balls from the Leaning Tower of Pisa is probably embellished, but the essence of the experiment is confirmed by Galileo’s other work.

1543 — Copernicus publishes On the Revolutions of the Heavenly Spheres

Description: Copernicus’s work was published shortly before the author’s death and at first provoked little opposition from the Church.

1572 — Tycho Brahe observes a new star, refuting the immutability of the heavens

Description: Tycho Brahe’s observation proved that the heavens are not unchanging, as had been believed since Aristotle.

1543 — Vesalius publishes On the Fabric of the Human Body

Description: Vesalius’s work corrected many anatomical errors inherited from Galen.

1545 — Cardano publishes solutions to cubic equations

Description: Cardano partly borrowed the formula for cubic equations from another mathematician, sparking one of the first major disputes over scientific priority.

Era VII. The Scientific Revolution (1600–1700)

1609 — Kepler publishes the first two laws of planetary motion

Description: Kepler derived his laws by processing Tycho Brahe’s vast body of observational data.

1610 — Galileo discovers the moons of Jupiter with a telescope

Description: Galileo was summoned before the Inquisition for these discoveries — they contradicted the official geocentric picture of the world.

1638 — Galileo publishes Discourses on Two New Sciences, laying the foundations of kinematics

Description: The book was written as a dialogue — a genre Galileo used later as well, with more tragic consequences.

1662 — Robert Boyle formulates the law relating the pressure and volume of a gas

Description: Boyle’s law became one of the first quantitative laws in the history of physics.

1687 — Newton publishes the Principia, the laws of motion and universal gravitation

Description: Many historians consider Newton’s Principia the most influential scientific book in history.

1704 — Newton publishes Opticks

Description: In this book Newton first described in detail the dispersion of light through a prism.

1661 — Boyle publishes The Sceptical Chymist, separating chemistry from alchemy

Description: The title of Boyle’s book literally means “the chemist who doubts [old theories].”

1608 — The telescope is invented in Holland

Description: The inventor of the telescope is not known with certainty — Hans Lippershey was the first to apply for a patent.

1609–1619 — Kepler publishes the three laws of planetary motion

Description: Kepler’s laws were the first to describe planetary orbits as elliptical rather than circular.

1610 — Galileo discovers the moons of Jupiter, the phases of Venus, and mountains on the Moon

Description: Galileo’s discoveries provided the first observational evidence for the heliocentric system.

1655 — Huygens discovers the rings of Saturn

Description: Huygens discerned Saturn’s rings thanks to a more powerful telescope he had built himself.

1687 — Newton’s law of gravitation explains planetary orbits

Description: Newton’s law of gravitation explained the motion of the planets by the same principles as the fall of an apple on Earth.

1665 — Hooke first describes cells while examining a slice of cork

Description: Hooke was the first to use the word “cell,” comparing the structures he saw to monks’ cells.

1668 — Redi experimentally refutes the spontaneous generation of flies

Description: Redi’s experiment with covered and uncovered jars of meat became one of the first examples of a controlled scientific experiment.

1677 — Leeuwenhoek first observes microorganisms

Description: Leeuwenhoek was the first in history to see unicellular organisms under a microscope, calling them “animalcules.”

1628 — Harvey describes the circulation of the blood

Description: Harvey calculated that the heart pumps an enormous volume of blood in a day — far too much for blood simply to be “consumed,” as had previously been thought.

1670s — Leeuwenhoek first observes bacteria under a microscope

Description: Leeuwenhoek discovered bacteria two centuries before scientists linked microbes to disease.

1614 — Napier invents logarithms

Description: Napier’s logarithms greatly simplified complex calculations long before calculators existed.

1637 — Descartes introduces coordinate (analytic) geometry

Description: Descartes’s analytic geometry first linked algebra and geometry through a coordinate system that now bears his name.

1654 — The correspondence of Pascal and Fermat lays the foundations of probability theory

Description: The Pascal–Fermat correspondence arose from a practical question — how to divide stakes fairly in an interrupted game of chance.

1665–1666 — Newton develops differential and integral calculus

Description: Newton developed much of the calculus during a forced isolation caused by a plague epidemic in Cambridge.

1675 — Leibniz independently develops calculus

Description: The priority dispute between Newton and Leibniz over the invention of calculus lasted for decades and divided mathematicians in Britain and continental Europe.

1687 — Newton applies calculus to planetary motion

Description: The modern notation of calculus (dx, dy, the integral) comes from Leibniz’s system, not Newton’s.

Era VIII. The Enlightenment and the Systematization of Knowledge (1700–1800)

1738 — Daniel Bernoulli lays the foundations of hydrodynamics

Description: Engineers still use Bernoulli’s equations when calculating an airplane wing.

1785 — Coulomb formulates the law of electrostatic interaction

Description: The unit of electric charge — the coulomb — is named in his honor.

1798 — Cavendish experimentally measures the gravitational constant

Description: Cavendish’s experiment is sometimes called “weighing the Earth.”

1754 — Joseph Black discovers carbon dioxide

Description: Carbon dioxide was the first distinct “kind of air” isolated and described in chemistry.

1774 — Priestley and Scheele independently discover oxygen

Description: Priestley and Scheele made the discovery almost simultaneously and independently of each other, a common occurrence in 18th-century science.

1777 — Lavoisier refutes the phlogiston theory

Description: The phlogiston theory dominated chemistry for nearly a century before it was finally overturned.

1789 — Lavoisier formulates the law of conservation of mass

Description: Lavoisier’s law of conservation of mass is often called the beginning of modern scientific chemistry.

1758 — The return of Halley’s Comet confirms a calculated prediction

Description: The comet named after Halley returns to Earth roughly once every 76 years.

1781 — William Herschel discovers the planet Uranus

Description: The discovery of Uranus was the first expansion of the Solar System beyond the planets known since antiquity.

1735 — Linnaeus publishes Systema Naturae, laying the foundations of biological taxonomy

Description: Linnaeus’s system, including the familiar division into genera and species, is still used by biologists with virtually no change.

1747 — Lind conducts one of the first controlled clinical experiments

Description: Lind found that citrus fruits cure scurvy — long before vitamin C itself was discovered.

1796 — Jenner develops vaccination against smallpox

Description: The word “vaccine” comes from the Latin name for the cow — Jenner used the cowpox virus.

1736 — Euler solves the Königsberg bridge problem, giving birth to graph theory

Description: The Königsberg bridge problem launched an entire field of mathematics — graph theory.

1799 — Gauss proves the fundamental theorem of algebra

Description: Gauss proved the theorem in his doctoral dissertation when he was only 21 years old.

Era IX. The 19th Century: Industrial Science

1800 — Volta invents the first electric battery

Description: Volta’s battery was the first source of continuous electric current in history.

1820 — Ørsted discovers a connection between electricity and magnetism

Description: Ørsted’s discovery was almost accidental — a compass needle twitched during a demonstration for students.

1831 — Faraday discovers electromagnetic induction

Description: The unit of electrical capacitance — the farad — is named after Faraday, who had no formal mathematical education.

1850 — Clausius formulates the second law of thermodynamics

Description: The second law of thermodynamics is sometimes called the law that explains why time flows only forward.

1865 — Maxwell publishes the equations of the electromagnetic field

Description: Maxwell’s equations were the first to show mathematically that light is an electromagnetic wave.

1887 — The Michelson–Morley experiment fails to detect the ether wind

Description: The negative result of this experiment is considered one of the key precursors of the theory of relativity.

1895 — Röntgen discovers X-rays

Description: Röntgen named the radiation he discovered “X-rays” because of its unknown nature — that is still the English name today.

1897 — J. J. Thomson discovers the electron

Description: The discovery of the electron first showed that the atom is not an indivisible particle.

1803 — Dalton formulates the atomic theory of matter

Description: Dalton derived atomic theory by studying the proportions in which elements combine with one another.

1811 — Avogadro formulates the law of the number of molecules in gases

Description: Avogadro’s law explained why equal volumes of different gases under the same conditions contain the same number of molecules.

1817 — Döbereiner describes “triads” of similar elements

Description: Döbereiner’s work anticipated the periodic system half a century before Mendeleev.

1828 — Wöhler synthesizes urea, refuting vitalism

Description: The synthesis of urea is considered the moment when organic chemistry ceased to be regarded as a domain beyond laboratory reproduction.

1834 — Faraday formulates the laws of electrolysis

Description: The laws of electrolysis became the foundation of modern electrochemistry and the industrial production of metals.

1846 — Schönbein discovers ozone

Description: The name “ozone” comes from the Greek word for “smelling” — the gas does indeed have a characteristic sharp odor.

1856 — Perkin synthesizes the first artificial dye

Description: Perkin’s dye was discovered by accident, during a failed attempt to synthesize a malaria drug.

1859–1860 — Bunsen and Kirchhoff invent the method of spectral analysis

Description: Spectral analysis made it possible for the first time to determine the chemical composition of stars, including the Sun.

1869 — Mendeleev publishes the periodic table of the chemical elements

Description: Mendeleev left empty spaces in the table and predicted the properties of as-yet-undiscovered elements — the predictions were confirmed.

1898 — The Curies discover radium and polonium

Description: Marie Curie became the first person to receive Nobel Prizes in two different scientific fields.

1838 — Bessel makes the first measurement of a star’s parallax

Description: Bessel’s parallax method made it possible for the first time to measure actual distances to stars.

1846 — Neptune is discovered through calculation, not direct observation

Description: The planet Neptune was computed mathematically before it was first seen through a telescope.

1859 — Kirchhoff and Bunsen lay the foundations of astronomical spectroscopy

Description: Spectral analysis of stars showed that they are composed of the same chemical elements as Earth.

1802 — The term “biology” is introduced to denote the science of living things

Description: The term “biology” was introduced independently by several European scientists.

1809 — Lamarck publishes one of the first theories of the evolution of species

Description: Lamarck incorrectly believed that traits acquired during life could be passed on to offspring.

1838–1839 — Schleiden and Schwann formulate cell theory

Description: Cell theory holds that all living organisms are composed of cells — the basic units of life.

1856–1863 — Mendel conducts experiments on pea hybridization

Description: Mendel conducted his experiments in a monastery garden, crossing more than 28,000 pea plants.

1859 — Darwin publishes On the Origin of Species

Description: Darwin delayed publishing the theory for nearly 20 years, fearing public reaction.

1861 — Pasteur experimentally refutes the spontaneous generation of life

Description: Pasteur’s experiments finally buried the idea of spontaneous generation, which had dominated for millennia.

1866 — Mendel’s laws of inheritance are published

Description: During Mendel’s lifetime his work went almost unnoticed by the scientific community.

1869 — Miescher discovers nucleic acid — the future DNA

Description: Miescher isolated DNA from the cell nuclei of pus-soaked bandages left over from operations.

1816 — Laennec invents the stethoscope

Description: The word “stethoscope” comes from the Greek words for “chest” and “to look.”

1842–1846 — Ether anesthesia is first used in surgery

Description: Before anesthesia, operations were performed with the patient conscious, often restrained by physical force.

1847 — Semmelweis shows a link between doctors washing their hands and maternal mortality

Description: Semmelweis’s contemporaries ridiculed him, and his idea was recognized only after his death.

1854 — John Snow stops a cholera epidemic in London, laying the foundations of epidemiology

Description: Snow identified the source of the epidemic by mapping cases in London — one of the first examples of medical statistics.

1867 — Lister introduces antisepsis into surgical practice

Description: Lister developed antisepsis independently of whether he knew of Pasteur’s germ theory at the time.

1882 — Koch discovers the causative agent of tuberculosis

Description: Koch formulated criteria for determining that a given microorganism causes a specific disease.

1885 — Pasteur tests a vaccine against rabies

Description: Pasteur tested the vaccine on a boy bitten by a rabid dog, even though he had no medical degree.

1895 — The discovery of X-rays gives rise to medical imaging

Description: Röntgen made the first medical radiograph in history — of his own wife’s hand.

1801 — Gauss publishes Disquisitiones Arithmeticae, laying the foundations of number theory

Description: Gauss is called the “prince of mathematicians” — according to legend, as a child he instantly added the numbers from 1 to 100.

1820s — Lobachevsky and Bolyai independently create non-Euclidean geometry

Description: Non-Euclidean geometry showed that Euclid’s parallel postulate is not the only possibility.

1854 — Boole formalizes the algebra of logic

Description: Boolean algebra became the foundation of the binary logic on which all modern computers are built.

1859 — Riemann formulates a hypothesis about the distribution of prime numbers

Description: The Riemann hypothesis remains one of the most important unsolved problems in modern mathematics.

1874 — Cantor creates set theory and introduces different sizes of infinity

Description: Cantor’s set theory met such fierce resistance from colleagues that it may have affected his mental health.

Era X. The Early 20th Century: Revolution in Physics (1900–1945)

1900 — Planck introduces the quantum of action

Description: Planck introduced the quantum reluctantly, regarding it more as a mathematical device than a physical reality.

1905 — Einstein publishes the special theory of relativity

Description: Special relativity was published when Einstein was only 26 years old.

1911 — Rutherford discovers the atomic nucleus

Description: Rutherford compared his discovery to firing a cannonball at tissue paper and finding something solid inside.

1915 — Einstein publishes the general theory of relativity

Description: General relativity predicted the curvature of spacetime — experimentally confirmed as early as 1919.

1927 — Heisenberg formulates the uncertainty principle

Description: The uncertainty principle states that one cannot know both the position and the velocity of a particle exactly at the same time.

1932 — Chadwick discovers the neutron

Description: The discovery of the neutron explained why atomic nuclei are heavier than one would expect from the number of protons alone.

1938 — Hahn and Strassmann discover nuclear fission

Description: This discovery became the foundation of both nuclear power and nuclear weapons.

1909 — Haber develops the industrial synthesis of ammonia from atmospheric nitrogen

Description: Haber’s ammonia synthesis made cheap fertilizers possible, but the same method was used to produce explosives.

1913 — Moseley introduces the concept of atomic number, refining the periodic law

Description: Moseley’s work explained anomalies in Mendeleev’s table, which had been based on atomic weight alone.

1916 — Lewis formulates the theory of the covalent chemical bond

Description: Lewis’s theory introduced the now-familiar “dots” for representing electron pairs in chemical formulas.

1932 — Heavy hydrogen — deuterium — is discovered

Description: Deuterium is almost twice as heavy as ordinary hydrogen because of an extra neutron in the nucleus.

1937 — Carothers synthesizes nylon

Description: Nylon became the first fully synthetic fiber produced on an industrial scale.

1908 — Leavitt discovers the relationship between the brightness and period of Cepheids

Description: Leavitt’s relation became the basis of the method for measuring distances to remote galaxies.

1915 — General relativity predicts the bending of light by gravity

Description: General relativity predicted an effect that did not exist in Newtonian physics.

1919 — Observation of a solar eclipse confirms general relativity

Description: The eclipse expedition was led by Arthur Eddington, who made Einstein’s theory world-famous.

1923 — Hubble proves that the Andromeda Nebula is a separate galaxy

Description: Before Hubble’s discovery, the entire visible universe was thought to be confined to the Milky Way.

1929 — Hubble discovers the expansion of the universe

Description: The discovery of the expanding universe became the foundation of the Big Bang theory.

1900 — Mendel’s laws are rediscovered, giving birth to genetics as a science

Description: Mendel’s work was rediscovered independently by three scientists in the same year.

1905 — The term “genetics” is introduced

Description: The word “genetics” comes from a Greek root meaning “origin.”

1910 — Morgan proves the chromosome theory of inheritance using fruit flies

Description: Morgan conducted experiments on Drosophila fruit flies — they have remained one of biology’s chief model organisms ever since.

1928 — Griffith conducts an experiment on bacterial transformation

Description: Griffith’s experiment first showed that some substance can transfer hereditary traits between bacteria.

1935 — The concept of the ecosystem is introduced into ecology

Description: The concept of the ecosystem united living organisms and their habitat into a single system of study.

1937 — The foundations of molecular biology are laid

Description: The term “molecular biology” was coined by a physicist, not a biologist — Warren Weaver.

1944 — Avery shows that DNA is the carrier of hereditary information

Description: Avery experimentally proved that the carrier of heredity is DNA, not proteins as previously thought.

1901 — Landsteiner discovers blood groups

Description: Landsteiner received the Nobel Prize for a discovery that made blood transfusion a safe procedure.

1921–1922 — Banting and Best discover insulin

Description: Before the discovery of insulin, a diagnosis of type 1 diabetes mellitus almost always meant death within a few years.

1928 — Fleming discovers penicillin

Description: Fleming noticed the effect of penicillin by accident — on a mold-contaminated dish that had spoiled an experiment.

1943 — Kolff creates the first “artificial kidney” machine

Description: Kolff’s machine was assembled from makeshift materials, including tin cans and a washing machine.

1948 — The World Health Organization is founded

Description: WHO was created as a specialized agency of the newly formed United Nations.

1900 — Hilbert formulates 23 unsolved problems of mathematics

Description: Of Hilbert’s 23 problems, some have been solved and some remain open to this day.

1931 — Gödel proves the incompleteness theorems

Description: Gödel’s theorems showed that in any sufficiently complex mathematical system there are statements that can be neither proved nor disproved.

1936 — Turing formalizes the notion of computability (the “Turing machine”)

Description: The Turing machine is a theoretical model that became the foundation of computability theory and modern computers.

Era XI. The Second Half of the 20th Century: Atoms, Genes, Space, and Computers

1947 — The transistor is invented at Bell Labs

Description: The transistor replaced bulky vacuum tubes and became the foundation of all modern electronics.

1964 — The Higgs boson is predicted

Description: The particle was jokingly nicknamed the “God particle” — Higgs himself was unenthusiastic about the nickname.

1951 — The first image of individual atoms is obtained

Description: The image of atoms was obtained by field ion microscopy — long before the invention of the scanning tunneling microscope.

1953 — Watson and Crick determine the chemical structure of DNA

Description: The DNA structure discovered by Watson and Crick used X-ray images by Rosalind Franklin, whose contribution was long undervalued.

1962 — Rachel Carson’s Silent Spring is published, marking the beginning of environmental chemistry

Description: Carson’s book is considered one of the main catalysts of the modern environmental movement.

1970s — Mass spectrometry becomes the principal method of molecular analysis

Description: Mass spectrometry makes it possible to determine the composition of a substance from the mass and charge of individual ions.

1985 — Fullerenes are discovered

Description: Fullerenes were named after the architect Buckminster Fuller for their resemblance to the spherical domes he designed.

1991 — Carbon nanotubes are discovered

Description: Carbon nanotubes are many times stronger than steel at a far lower density.

1995 — The first atom of antimatter is synthesized

Description: The antihydrogen atom existed for only a tiny fraction of a second before annihilating.

1957 — The first artificial Earth satellite is launched

Description: The satellite launch marked the beginning of the space age and the space race.

1965 — Cosmic microwave background radiation is discovered, confirming the Big Bang theory

Description: The cosmic microwave background was discovered by accident — engineers first took the signal for interference from pigeon droppings in the antenna.

1969 — Humans land on the Moon for the first time

Description: The first to set foot on the Moon were the astronauts of the Apollo 11 mission in 1969.

1990 — The Hubble Space Telescope is launched

Description: Despite a mirror defect at launch, Hubble after repair became one of the most productive telescopes in history.

1995 — The first exoplanet around a Sun-like star is discovered

Description: Since 1995, scientists have confirmed the existence of thousands of exoplanets.

1953 — Watson and Crick discover the double-helix structure of DNA

Description: The double-helix model was built in large part thanks to X-ray images by Rosalind Franklin.

1961 — The genetic code is deciphered

Description: Deciphering the genetic code showed that it is virtually universal for all living organisms on Earth.

1970 — Restriction enzymes are discovered — the foundation of genetic engineering

Description: The discovery of restriction enzymes gave scientists “molecular scissors” for working with DNA.

1973 — The first recombinant DNA molecule is created

Description: The first recombinant DNA combined genes from entirely different species of organisms.

1975 — The Asilomar conference sets ethical frameworks for genetic engineering

Description: At the Asilomar conference, scientists voluntarily paused some experiments until safety rules were developed.

1977 — Sanger develops a method of DNA sequencing

Description: Sanger sequencing remained the principal method of DNA sequencing for nearly 30 years.

1983 — Mullis invents the polymerase chain reaction (PCR)

Description: Mullis said the idea for the method came to him during a nighttime drive along a California highway.

1990 — The international Human Genome Project is launched

Description: The Human Genome Project brought together scientists from six countries and cost several billion dollars.

1996 — Dolly the sheep is cloned — the first cloned mammal

Description: Dolly lived only six and a half years — less than the average lifespan of sheep of her breed.

1952 — Salk develops a vaccine against polio

Description: The Salk vaccine was tested in the largest medical study in U.S. history up to that time.

1954 — The first successful kidney transplant is performed

Description: The first kidney transplant was performed between identical twins, which solved the problem of rejection.

1967 — Barnard performs the first human heart transplant

Description: Barnard’s first heart-transplant patient lived only 18 days after the operation.

1978 — The first person conceived by IVF is born

Description: The birth of the “test-tube baby” sparked intense ethical debates that continue in various forms today.

1980 — WHO declares the complete eradication of smallpox worldwide

Description: Smallpox remains the only human infectious disease fully eradicated by medical effort.

1981 — The first clinical cases of AIDS are described

Description: The first cases of AIDS were described as a rare cluster of unusual infections in several patients.

1996 — Combination antiretroviral therapy changes the course of HIV infection

Description: Combination therapy first turned HIV infection from a death sentence into a manageable chronic disease.

1990 — The first successful human gene therapy is performed

Description: The first approved gene-therapy protocol was applied to a four-year-old girl with a rare immune disorder.

1948 — Shannon lays the foundations of information theory

Description: Shannon’s information theory introduced the “bit” as a unit of information.

1976 — The four color theorem is proved for the first time with the help of a computer

Description: The proof of the four color theorem required a computer to check thousands of cases — many mathematicians at first refused to accept such a proof as “real.”

1994 — Wiles proves Fermat’s Last Theorem

Description: Wiles worked on the proof in secret for nearly seven years before presenting it to the public.

Era XII. The 21st Century: Genomics, AI, and Climate

2012 — The Higgs boson is experimentally detected at the Large Hadron Collider

Description: Confirmation of the Higgs boson completed nearly half a century of searching for the last missing particle of the Standard Model.

2003 — The sequencing of the human genome by chemical methods is completed

Description: Sequencing the human genome took more than ten years of international collaboration.

2010 — The Nobel Prize is awarded for research on graphene

Description: Graphene is a material one carbon atom thick, with record strength and electrical conductivity.

2016 — The synthesis of elements 113–118 completes the seventh period of the periodic table

Description: The synthesized superheavy elements exist for only fractions of a second before decaying.

2015 — Gravitational waves are detected for the first time

Description: The discovery of gravitational waves confirmed the last of the key predictions of Einstein’s general theory of relativity.

2019 — The first image of a black hole is obtained

Description: The black-hole image was produced by combining data from telescopes around the world into a single virtual telescope the size of Earth.

2003 — The sequencing of the human genome is completed

Description: Completing the genome sequence took several years longer and cost many times more than originally expected.

2012 — The CRISPR method of genome editing is developed

Description: CRISPR was discovered as part of the bacterial immune system that protects bacteria from viruses.

2022 — A fully completed human genome sequence is published

Description: The 2022 final version of the genome was the first to fill previously “empty” and hard-to-read stretches of DNA.

2003 — The SARS outbreak — the first major epidemic of the 21st century

Description: The name SARS stands for “severe acute respiratory syndrome.”

2020 — The COVID-19 pandemic spreads across the world

Description: The COVID-19 pandemic was the first pandemic of this scale in the age of global air travel.

2020 — mRNA vaccines against COVID-19 are developed in record time

Description: mRNA vaccines were developed faster than any vaccine in the history of medicine — thanks to decades of prior research on the technology.

2003 — Perelman proves the Poincaré conjecture

Description: For solving the Poincaré conjecture Perelman was awarded a million-dollar prize, which he declined.

2022 — AI systems begin to be applied to the search for mathematical proofs

Description: AI systems already help mathematicians find counterexamples and suggest directions for new proofs.